2016-02-10

arbete ”Dynamic Contrast-Enhanced and Intravoxel Incoherent Motion. MRI analysis for carbon-ion beams radiation treatment monitoring in.

Abstract Purpose: To systematically analyze intravoxel incoherent motion (IVIM) MRI in a perfusable capillary phantom closely matching the geometry of capillary beds in vivo and to compare the validity of the biexponential pseudo-diffusion and the recently introduced phase-distribution IVIM model. At very low diffusion weighting the diffusion MRI signal is affected by intravoxel incoherent motion (IVIM) caused by dephasing of magnetization due to incoherent blood flow in capillaries or other sources of microcirculation. The aim of the study was to compare intravoxel incoherent motion diffusion-weighted imaging (DWI) for evaluating lung cancer using single-shot turbo spin-echo (TSE) and single-shot echo-planar imaging (EPI) in a 3T MR system. Intravoxel incoherent motion (IVIM) can be seen as subfield of diffusion MRI. It allows tissue microcirculation (perfusion) to be investigated in addition to tissue microstructure (from molecular diffusion).

Intravoxel

IVIM DW-MRI is currently used widely to characterize various diseases.1,3–5 MRI is also an excellent noninvasive modality for evaluating bone marrow A Combined Use of Intravoxel Incoherent Motion MRI Parameters Can Differentiate Early-Stage Hepatitis-b Fibrotic Livers from Healthy Livers Yì Xiáng J. Wáng 1*, Min Deng , Yáo T. Li1, Hua Huang2, Jason Chi Shun Leung3, Weitian Chen1, and Pu-Xuan Lu4* Abstract Intravoxel incoherent motion (IVIM) imaging is a concept and a method initially introduced and developed by Le Bihan et al. to quantitatively assess all the microscopic translational motions that could contribute to the signal acquired with diffusion MRI. Background and purpose: Intravoxel incoherent motion MR imaging can simultaneously measure the diffusion and perfusion characteristics of brain tumors. Our aim was to determine the utility of intravoxel incoherent motion-derived perfusion and diffusion parameters for assessing the treatment response of metastatic brain tumor following gamma knife radiosurgery. 2019-09-30 · 1. Neuroimage. 2019 Sep 30;204:116228. doi: 10.1016/j.neuroimage.2019.116228.

Liver intravoxel incoherent motion (IVIM) magnetic resonance imaging: a comprehensive review of published data on normal values and applications for fibrosis

The model assumes two compartments: a slow moving compartment 1. Radiology.

2016-07-07 · Objective Intravoxel incoherent motion (IVIM) is an MRI technique with potential applications in measuring brain tumor perfusion, but its clinical impact remains to be determined. We assessed the usefulness of IVIM-metrics in predicting survival in newly diagnosed glioblastoma. Methods Fifteen patients with glioblastoma underwent MRI including spin-echo echo-planar DWI using 13 b-values

to quantitatively assess all the microscopic translational motions that could contribute to the signal acquired with diffusion MRI. Background and purpose: Intravoxel incoherent motion MR imaging can simultaneously measure the diffusion and perfusion characteristics of brain tumors. Our aim was to determine the utility of intravoxel incoherent motion-derived perfusion and diffusion parameters for assessing the treatment response of metastatic brain tumor following gamma knife radiosurgery.

The intravoxel incoherent motion (IVIM) theory, proposed by Le Bihan et al. 3, enables evaluation of living tissue diffusion movement and micro-vessel perfusion in vivo using quantitative Background As both intravoxel incoherent motion (IVIM) modeling and dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) provide perfusion parameters, IVIM‐derived perfusion parameters might be expected to correlate with the kinetic features from DCE‐MRI. To address these issues, this paper develops an intravoxel incoherent motion- (IVIM-) MRI-based histogram analysis approach, which takes advantage of several hyperspectral techniques, such as the band expansion process (BEP), to expand a multispectral image to hyperspectral images and create an automatic target generation process (ATGP). Intravoxel incoherent motion imaging was performed on a 3 T magnetic resonance imaging scanner using 15 b values (0–800 s/mm 2) for 4 phantoms with different area fractions of the flowing water compartment (FWC%), at the infusion flow rates of 0, 1, 2, and 3 mL/min. Images were quantitatively analyzed using monoexponential free biexponential, and segmented biexponential fitting models.
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Both single-shot TSE-DWI and single-shot EPI-DWI were scanned twice respectively for 15 patients with lung cancer. Göteborg,2018 Intravoxel incoherent motion modeling Optimization of acquisition, analysis and tumor tissue characterization Oscar Jalnefjord DepartmentofRadiationPhysics,InstituteofClinicalSciences, Objective To determine if intravoxel incoherent motion (IVIM) magnetic resonance perfusion can measure the quality of the collateral blood flow in the penumbra in hyperacute stroke.

MATERIALS AND METHODS: The study cohort included 123 head and neck tumors: 30 SCCs, 28 benign and 20 malignant SG tumors, 36 lymphomas, and 9 schwannomas. The D and PP values were Diffusion and Intravoxel Incoherent Motion MR Imaging–based Virtual Elastography: A Hypothesis-generating Study in the Liver. Denis Le Bihan, Shintaro Ichikawa, Utaroh Motosugi; Denis Le Bihan , Shintaro Ichikawa, Utaroh Motosugi 2019-12-24 · Currently, little is known regarding the value of quantitative parameters derived from the intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) with integrated slice-specific Intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI), with a bi-exponential model, can not only observe the diffusion of tissue water molecules but also reflect the blood perfusion information of tissue microcirculation, compensating for the deficiencies of conventional DWI [15] . Multiparametric intravoxel incoherent motion (IVIM) provides diffusion and perfusion information for the treatment prediction of cancer.
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A Combined Use of Intravoxel Incoherent Motion MRI Parameters Can Differentiate Early-Stage Hepatitis-b Fibrotic Livers from Healthy Livers Yì Xiáng J. Wáng 1, Min Deng , Yáo T. Li1, Hua Huang2, Jason Chi Shun Leung3, Weitian Chen1, and Pu-Xuan Lu4 Abstract

The requisites and challenges of quantitative evaluation beyond simple monoexponential relationships are Intravoxel incoherent motion (IVIM) is a magnetic resonance imaging (MRI) technique that extracts microvascular perfusion information from a multi-b value diffusion-weighted imaging (DWI) sequence.